555 research outputs found

    A New Reduced Basis Method for Parabolic Equations Based on Single-Eigenvalue Acceleration

    Full text link
    In this paper, we develop a new reduced basis (RB) method, named as Single Eigenvalue Acceleration Method (SEAM), for second-order parabolic equations with homogeneous Dirichlet boundary conditions. The high-fidelity numerical method adopts the backward Euler scheme and conforming finite elements for the temporal and spatial discretization, respectively. Under the assumption that the time step size is sufficiently small and time steps are not very large, we show that the singular value distribution of the high-fidelity solution matrix UU is close to that of a rank one matrix. We select the eigenfunction associated with the principal eigenvalue of the matrix U⊤UU^\top U as the basis of the Proper Orthogonal Decomposition (POD) method to obtain SEAM and a parallel SEAM. Numerical experiments confirm the efficiency of the new method

    Preparation and characterization of antigenic properties of gramicidin A- keyhole limpet hemocyanin and gramicidin A- ovalbumin conjugates

    Get PDF
    A rapid, simple and low cost procedure for preparing hapten-protein conjugates was developed using gramicidin A (GA) and two other water-soluble proteins, keyhole limpet hemocyanin (KLH) and ovalbumin (OVA). GA was a kind of antimicrobial peptides. Two lysines and a cysteine were linked to amino- terminus and carboxyl-terminus of the peptide chain, respectively, in order to form sulfhydryl groups and improve its water solubility. And the molecule weight and purity of the modified peptidechain were checked by electron spray ionization mass spectrometry (ESI-MS) and high performance liquid chromatography (HPLC). Then the activated KLH and OVA were conjugated to GA by using  4-(Nmaleimidomethyl) cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt (sulfo-SMCC) to form disulfide linkage. In order to obtain artificial antigen of GA, GA was linked to KLHand OVA by sulfo-SMCC coupling at room temperature. The conjugates of KLH-Peptide and OVAPeptide were identified by infrared and ultraviolet spectrophotometry SDS-PAGE and DTNB method, which could prove the activity of the sulfhydryl-groups. In this way, we have obtained a novel artificial immunogen and coating antigen that could be used to raise polyclonal antibody through immunized rabbits

    Lidar with Velocity: Correcting Moving Objects Point Cloud Distortion from Oscillating Scanning Lidars by Fusion with Camera

    Full text link
    Lidar point cloud distortion from moving object is an important problem in autonomous driving, and recently becomes even more demanding with the emerging of newer lidars, which feature back-and-forth scanning patterns. Accurately estimating moving object velocity would not only provide a tracking capability but also correct the point cloud distortion with more accurate description of the moving object. Since lidar measures the time-of-flight distance but with a sparse angular resolution, the measurement is precise in the radial measurement but lacks angularly. Camera on the other hand provides a dense angular resolution. In this paper, Gaussian-based lidar and camera fusion is proposed to estimate the full velocity and correct the lidar distortion. A probabilistic Kalman-filter framework is provided to track the moving objects, estimate their velocities and simultaneously correct the point clouds distortions. The framework is evaluated on real road data and the fusion method outperforms the traditional ICP-based and point-cloud only method. The complete working framework is open-sourced (https://github.com/ISEE-Technology/lidar-with-velocity) to accelerate the adoption of the emerging lidars

    Ultrafast Charge Transfer in Atomically Thin MoS2/WS2 Heterostructures

    Full text link
    Van der Waals heterostructures have recently emerged as a new class of materials, where quantum coupling between stacked atomically thin two-dimensional (2D) layers, including graphene, hexagonal-boron nitride, and transition metal dichalcogenides (MX2), give rise to fascinating new phenomena. MX2 heterostructures are particularly exciting for novel optoelectronic and photovoltaic applications, because 2D MX2 monolayers can have an optical bandgap in the near-infrared to visible spectral range and exhibit extremely strong light-matter interactions. Theory predicts that many stacked MX2 heterostructures form type-II semiconductor heterojunctions that facilitate efficient electron-hole separation for light detection and harvesting. Here we report the first experimental observation of ultrafast charge transfer in photo-excited MoS2/WS2 heterostructures using both photoluminescence mapping and femtosecond (fs) pump-probe spectroscopy. We show that hole transfer from the MoS2 layer to the WS2 layer takes place within 50 fs after optical excitation, a remarkable rate for van der Waals coupled 2D layers. Such ultrafast charge transfer in van der Waals heterostructures can enable novel 2D devices for optoelectronics and light harvesting

    Systematic Determination of Absolute Absorption Cross-section of Individual Carbon Nanotubes

    Full text link
    Determination of optical absorption cross-section is always among the central importance of understanding a material. However its realization on individual nanostructures, such as carbon nanotubes, is experimentally challenging due to the small extinction signal using conventional transmission measurements. Here we develop a technique based on polarization manipulation to enhance the sensitivity of single-nanotube absorption spectroscopy by two-orders of magnitude. We systematically determine absorption cross-section over broad spectral range at single-tube level for more than 50 chirality-defined single-walled nanotubes. Our data reveals chirality-dependent one-dimensional photo-physics through the behaviours of exciton oscillator strength and lifetime. We also establish an empirical formula to predict absorption spectrum of any nanotube, which provides the foundation to determine quantum efficiencies in important photoluminescence and photovoltaic processes
    • …
    corecore